Half-Year 2022 Financial and Clinical Trials Update slide image

Half-Year 2022 Financial and Clinical Trials Update

PRED oncology development programs -2 Roche Molecule Indication Phase # of patients Status CT Identifier Oncology Solid tumors | 110 FPI Q4 2019 NCT04158583 CD25 (RG6292) Advanced and metastatic solid Part I: FPI Q1 2021 160 NCT04642365 tumors Part II: FPI Q4 2021 Anti-GPRC5D (RG6234) Multiple myeloma 240 FPI Q4 2020 NCT04557150 HLA-A2-WT1 x CD3 (RG6007) AML | 160 FPI Q4 2020 FAP-CD40 (RG6189) Solid tumors 280 FPI Q2 2021 HLA-A2-MAGE-A4 x CD3 (RG6129) Solid tumors 180 FPI Q1 2022 NCT04580121 NCT04857138 NCT05129280 BRAFI (3) (RG6344) Solid tumors 292 FPI Q1 2022 FPI Q1 2022 CD19xCD28 (RG6333) R/R B cell non-Hodgkin's lymphoma | ~200 ISRCTN13713 551 NCT05219513 Combination study with glofitamab EGFRvlllxCD3 (RG6156) Glioblastoma ~200 FPI Q2 2022 NCT05187624 151
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