BenevolentAI Investor Day Presentation Deck

BenevolentAl's target discovery tools and process identifies promising, novel therapeutic targets TECH APPROACH PREDICT TRIAGE ΤΡΑ ASSAY 1. Define the Tech Approach Using our in-house tools and algorithms we explore the data and define the input to our predictive models 3. Triage and Assess Progressibility Can we treat ALS by reversing Autophagy impairment in microglia by reducing oxidative stress? Our tools aggregate and present the necessary data for scientific decision- making, progressing only the most promising hypotheses. Sign 120 Disease Target 120 C Mechanism CARMI PDK1 ULK1 Endpoint: What we are measuring in the assay NR1H3 Cell type P 1 G * 2. Target Prediction Our Al algorithms, data queries, and endotype-driven workflows identify targets that are likely to address the tech approach. Graph Models Transcriptomics Models Precision Medicine Genetics 2. Target ID Precision Medicine 'Omics Data queries Large Language Model Aggregation Prioritization Targets 4. Validate Experimentally Targets sent to a series of mechanistic and disease-relevant assays to assess a target's potential. Benevolent 34

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