AbCellera IPO Presentation Deck
DEEPLY SEARCH ANY
ANTIBODY RESPONSE WITH
MICROFLUIDIC
SINGLE-CELL
ASSAYS
1251
張
0000 0000 0000 0000
Multiple credit card-sized devices
integrating 512K miniaturized chambers
per setup to screen millions of B cells.
SOURCE
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FIND
ANALYZE ENGINEER
<1nL single-cell chamber
x 256,000 per device
Each B cell is tested for the secretion of
antibodies that bind to specific antigens.
Positive binding is detected by high-throughput
fluorescence microscopy and processed using
machine vision.
EXEMPLARY ASSAY:
BEAD-BASED MULTIPLEX
Secreted
Antibodies
Antibody-
Secreting Cell
Brightfield
ASSAY DESIGN SIDE VIEW
READOUT TOP VIEW
Optical Bead
Encoding
Labelled
Secondary
Antibodies
Antigen-Coated
Beads (A. B. C)
Binding with
Encoding MaskView entire presentation