AbCellera IPO Presentation Deck slide image

AbCellera IPO Presentation Deck

DEEPLY SEARCH ANY ANTIBODY RESPONSE WITH MICROFLUIDIC SINGLE-CELL ASSAYS 1251 張 0000 0000 0000 0000 Multiple credit card-sized devices integrating 512K miniaturized chambers per setup to screen millions of B cells. SOURCE SEARCH FIND ANALYZE ENGINEER <1nL single-cell chamber x 256,000 per device Each B cell is tested for the secretion of antibodies that bind to specific antigens. Positive binding is detected by high-throughput fluorescence microscopy and processed using machine vision. EXEMPLARY ASSAY: BEAD-BASED MULTIPLEX Secreted Antibodies Antibody- Secreting Cell Brightfield ASSAY DESIGN SIDE VIEW READOUT TOP VIEW Optical Bead Encoding Labelled Secondary Antibodies Antigen-Coated Beads (A. B. C) Binding with Encoding Mask
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