40th Annual J.P. Morgan Healthcare Conference Presentation

2020 & 2019 Reconciliation Net Income Per Share R REPLIGEN Reconciliation of GAAP Net Income per Share to Non-GAAP (Adjusted) Net Income per Share (Unaudited) GAAP Net Income per Share - DILUTED Adjustments to Net Income per Share - DILUTED Acquisition and integration costs Inventory step-up charges Intangible amortization Loss on extinguishment of debt Non-cash interest expense Tax effect of intangible amortization and acquisition costs Adjusted Net Income per Share - DILUTED Totals may not add due to rounding $ es $ es Ś $ $ $ $ $ Twelve Months Ended December 31, 2020 1.11 0.19 0.01 0.30 0.20 (0.17) $1.65 $ $ $ $ $ $ $ $ 2019 0.44 0.26 0.03 0.27 0.11 0.15 (0.20) 1.07 21

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