Roche Pharmaceutical Development and Sales Overview slide image

Roche Pharmaceutical Development and Sales Overview

2022: Key late-stage news flow* and upcoming IR events Regulatory Phase III/ pivotal readouts Compound Vabysmo Susvimo Lunsumio (mosunetuzumab) Tecentriq Hemlibra Polivy + R-CHP glofitamab Tecentriq + tiragolumab + chemo Tecentriq + chemo Tecentriq + tiragolumab Tecentriq giredestrant Tecentriq + Avastin Venclexta + dexamethasone Tecentriq + chemo Tecentriq + tiragolumab + chemo Alecensa gantenerumab Susvimo Vabysmo Indication nAMD/DME nAMD 3L+ FL Adjuvant NSCLC Mild to moderate hemophilia A 1L DLBCL 3L+ DLBCL 1L ES-SCLC Adjuvant SCCHN 1L PDL 1+ NSCLC Adjuvant RCC 2/3L HR+ MBC Adjuvant HCC t(11;14) R/R MM Periadjuvant NSCLC 1L esophageal cancer Adjuvant ALK+ NSCLC Alzheimer's disease DME / DR RVO Milestone US/EU approval EU approval US/EU approval EU approval EU approval EU/US approval Ph lb NP30179 Ph III SKYSCRAPER-02 Ph III IMvoke010 Ph III SKYSCRAPER-01 Ph III IMmotion010 Ph II acelERA Ph III IMbrave050 Delayed EU EU × 2023 Continues to OS IA Х 2023 Ph III CANOVA Ph III IMpower030 2023 Ph III SKYSCRAPER-08 (China only) 2023 Ph III ALINA 2023 Ph III GRADUATE 1/2 Ph III PAGODA / PAVILION Ph III BALATON/COMINO Virtual event Angiogenesis Monday, 14 Feb 16:30 to 17:45 CEST Virtual event MDA Wednesday, 16 Mar 16:30 to 17:30 CEST Roche ESG Day Access to Healthcare Monday, 16 May 15:00 to 16:30 CEST Virtual event ASCO Monday, 6 Jun 16:00 to 17:30 CEST Roche Pharma Day London Monday, 12 Sep 10:30 to 15:00 BST Virtual event ASH Wednesday, 14 Dec 16:00 to 17:30 CET * Outcome studies are event-driven: timelines may change; OS-overall survival; IA=interim analysis Roche 32
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