41st Annual J.P. Morgan Healthcare Conference

Strong revenue growth driven by innovation and portfolio expansion Analytics ~$57M 7% Chroma $36M 26% 2017 $141M Revenue R REPLIGEN Filtration $49M 35% Proteins $54M 38% 2017-2022 34% 5-year avg. annual organic growth Chroma ~$125M 16% Proteins ~$110M 14% 2022e $800M Revenue Filtration ~$505M 63% Long life-cycle, highly differentiated systems and consumable products 2022e total revenue reflects guidance midpoint as of our Q3 earnings call Nov. 1, 2022. 2022e franchise-level revenue and percent of total reflect franchise-level growth estimates as of our Q3 earnings call Nov. 1, 2022. 5

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